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KMID : 0371620010160010113
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Journal of Wonkwang Medical Science
2001 Volume.16 No. 1 p.113 ~ p.117
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Tree Cases of Thyrotoxic Periodic Paralysis
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Choi Ji-Hun
Choi Kyoung-Suk
Kim Ki-Hoon
Park Byoung-Hyun
Cho Chung-Gu
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Abstract
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Thyrotoxic periodic paralysis is characterized by intermittent flaccid paralysis of skeletal muscle, lasting several hours. The underlying pathophysiology of the syndrome is not yet to be well characterized and remains controversal, but reflects altered potassium and calcium dynamics as well as certain morphologic characteristics within the muscle unit itself. It occurs primarily in Asian populations with an overwhelming male preponderance and a higher association of specific HLA antigens. Precipitating factors include high carbohydrate ingestion, exercise, trauma, infection, alcohol ingestion, administration of epinephrine, thyroid hormone, or corticosteroid. If hypokalemia is present, potassium administration may help abort the attack, but the only definitive treatment is formation of euthyroid state. We discribed two patients with hypokalemic thyrotoxic periodic paralysis and one patient with normokalemic thyrotoxic periodic paralysis.
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KEYWORD
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thyrotoxicosis, periodic paralysis
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